On Top Of The World Paper Trail T.I.

we see Samuel Jackson like what's up motherfucker

Ludacris mentions that rappers are often multi-talented and can do many other things including acting. He's saying that famous actor Samuel L. Jackson should watch out, because rappers may be on the same stage as him accepting Oscar awards soon.
bill
I also think Samuel L Jackson and the term "(bad ass) mother fucker" are nearly synonymous since the movie 'Pulp Fiction'. So I don't think Luda means any ill will.
ms. d-dizzle